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| January 9, 1988 | So Emotional | Whitney Houston |
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| January 16, 1988 | Got My Mind Set On You | George Harrison |
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| January 23, 1988 | The Way You Make Me Feel | Michael Jackson |
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| January 30, 1988 | Need You Tonight | INXS |
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| February 6, 1988 | Could've Been | Tiffany |
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| February 20, 1988 | Seasons Change | Expose |
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| February 27, 1988 | Father Figure | George Michael |
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| March 12, 1988 | Never Gonna Give You Up | Rick Astley |
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| March 26, 1988 | Man In The Mirror | Michael Jackson |
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| April 9, 1988 | Get Outta My Dreams, Get Into My Car | Billy Ocean |
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| April 23, 1988 | Where Do Broken Hearts Go | Whitney Houston |
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| May 7, 1988 | Wishing Well | Terrence Trent D'Arby |
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| May 14, 1988 | Anything For You | Gloria Estefan & Miami Sound Machine |
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| May 28, 1988 | One More Try | George Michael |
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| June 18, 1988 | Together Forever | Rick Astley |
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| June 25, 1988 | Foolish Beat | Debbie Gibson |
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| July 2, 1988 | Dirty Diana | Michael Jackson |
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| July 9, 1988 | The Flame | Cheap Trick |
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| July 23, 1988 | Hold On To The Nights | Richard Marx |
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| July 30, 1988 | Roll With It | Steve Winwood |
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| August 27, 1988 | Monkey | George Michael |
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| September 10, 1988 | Sweet Child Of Mine | Guns N' Roses |
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| September 24, 1988 | Don't Worry Be Happy | Bobby McFerrin |
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| October 8, 1988 | Love Bites | Def Leppard |
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| October 15, 1988 | Red Red Wine | UB40 |
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| October 22, 1988 | Groovy Kind Of Love | Phil Collins |
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| November 5, 1988 | Kokomo | The Beach Boys |
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| November 12, 1988 | Wild Wild West | The Escape Club |
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| November 19, 1988 | Bad Medicine | Bon Jovi |
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| December 3, 1988 | Baby I Love Your Way / Freebird Medley | Will To Power |
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| December 10, 1988 | Look Away | Chicago |
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| December 24, 1988 | Every Rose Has It's Thorn | Poison |
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